What is expandable creative?
A creative which expands under any action (mouse over, click, automatic) in any kind of directions, taking a lot of view space on a page. For correct execution of expandable creative, you need iFrame to be supported on a domain.

How iframe affects expandable creatives?

There are 2 types of iFrame in a render of correct creative expand - Friendly and Non-friendly. 

When expandable creative is showing in the non-friendly iFrame it is unable to expand it outside the browser boundaries according to its policy. But, if the iFrame domain supports the same iFrame Buster technology as an expandable creative do - it will work correctly.

Reports

Possible iFrame states (not detected):

Content tags
In order to be able to bid on expandable inventory you should put one of the next content tags depending on your creative expand behavior: